1998.09-2002.07 同濟大學(xué) 環(huán)境工程 學(xué)士

2002.09-2007.07 清華大學(xué) 環(huán)境工程 博士

2009.07-至今          清華大學(xué) 環(huán)境學(xué)院 講師、副教授、長聘副教授

2014.02-2014.11      英國南安普頓大學(xué)光電中心 訪問學(xué)者

2008.09-2009.03    加拿大阿爾伯塔大學(xué) 訪問學(xué)者

2007.07-2009.06    清華大學(xué) 博士后

環(huán)境監(jiān)測、環(huán)境污染物生物化學(xué)分析技術(shù)、生物傳感器及納米生物傳感器

1. 國家自然科學(xué)基金重大項目，環(huán)境介質(zhì)中的病毒識別與傳播規(guī)律，2021/01-2025/12，在研，參加

2. 清華大學(xué)春風(fēng)基金抗疫專項，CRISPR/Cas13a結(jié)合核酸自驅(qū)動放大的病毒現(xiàn)場檢測試紙條及其定量檢測裝置，2020/09-2022/09，在研，主持

3. 中國工程院應(yīng)急科技攻關(guān)項目，城市水系統(tǒng)關(guān)鍵節(jié)點新型冠狀病毒存在風(fēng)險識別，2020/02-2021/02，結(jié)題，參加

4. 國家自然科學(xué)基金面上基金項目，分子對接輔助優(yōu)化水中環(huán)境雌激素擬/抗活性同步檢測的生物傳感分析技術(shù)，2020/01-2023/12，在研，主持

5. 國家重點研發(fā)計劃，村鎮(zhèn)社區(qū)環(huán)境監(jiān)測及修復(fù)關(guān)鍵技術(shù)研發(fā)，2019/11-2022/12，在研，參加

6. 國家重點研發(fā)計劃，場地地下水污染快速識別與風(fēng)險監(jiān)測管控技術(shù)，2020/01-2022/12，在研，參加

7. EPSC自由申請課題，微囊藻毒素廣譜性抗體篩選及其倏逝波免疫傳感分析應(yīng)用，2019/08-2021/08，結(jié)題，主持

8. 北京市自然科學(xué)基金-海淀原始創(chuàng)新聯(lián)合基金重點項目，水中抗生素快速定量檢測的倏逝波生物傳感分析技術(shù)，2019/01-2021/12，結(jié)題，主持

9. 清華大學(xué)-劍橋大學(xué)聯(lián)合科研基金，功能化二維材料表面等離子體共振增強機制及其用于環(huán)境雌激素傳感分析研究，2019/01-2021/07，結(jié)題，主持

10. 北京市自然科學(xué)基金面上項目，基于受體的再生水中雌激素效應(yīng)檢測倏逝波熒光傳感技術(shù)，2018/01-2019/12，結(jié)題，主持

11. EPSC聯(lián)合基金，核受體介導(dǎo)的環(huán)境內(nèi)分泌干擾物效應(yīng)檢測生物傳感器技術(shù)，2017/05-2019/04，結(jié)題，聯(lián)合主持

12. 國家自然科學(xué)基金中英合作交流項目，用于環(huán)境生物檢測的多通道集成光波導(dǎo)芯片，2017/04-2019/03，結(jié)題，主持

13. 國家自然科學(xué)基金面上基金項目，基于工程化適配體的水中抗生素快速定量倏逝波傳感檢測技術(shù)，2017/01-2020/12，結(jié)題，主持

14. 國家科技部重大儀器開發(fā)專項，多指標平面波導(dǎo)生物芯片的開發(fā)，2012/09-2017/09，結(jié)題，參與

15. 國家科技部863計劃，水質(zhì)安全生物預(yù)警監(jiān)測技術(shù)與系統(tǒng)，2014/01-2017/12，結(jié)題，參加

16. 北京市自然科學(xué)基金項目，基于微電極測試的污水深度處理反硝化生物濾池脫氮模型，2013/01-2015/12，結(jié)題，主持

17. 清華大學(xué)國際科技合作項目，基于功能核酸的重金屬檢測技術(shù)研究，2013/01-2014/12，結(jié)題，主持

18. 國家自然科學(xué)基金青年基金，人工金屬氧化物納米顆粒在污水生物處理系統(tǒng)中的歸趨及對微生物聚集體活性的影響，2012/01-2014/12，結(jié)題，負責(zé)人

2021年 總微囊藻毒素在線分析儀，中國發(fā)明協(xié)會發(fā)明創(chuàng)業(yè)獎創(chuàng)新獎二等獎/第48屆日內(nèi)瓦國際發(fā)明展會金獎，排名第一

2020年 中國產(chǎn)學(xué)研合作創(chuàng)新獎、中國儀器儀表學(xué)會朱良漪分析儀器青年創(chuàng)新獎、國家生態(tài)環(huán)境保護專業(yè)技術(shù)青年拔尖人才

2015年 清華大學(xué)環(huán)境學(xué)院學(xué)生工作先進個人

2014年 微量有毒污染物快速高靈敏檢測的生物傳感技術(shù)及儀器，教育部技術(shù)發(fā)明獎一等獎，排名第六

2014年 入選“清華大學(xué)桑坦德銀行資助項目”

2014年《污水處理在線監(jiān)測儀器原理與應(yīng)用（第二版）》獲得“2014年中國石油和化學(xué)工業(yè)優(yōu)秀出版物獎·圖書獎”二等獎（排名第二）

2011年 教育部“長江學(xué)者和創(chuàng)新團隊發(fā)展計劃”創(chuàng)新團隊，成員

以第一/通訊作者在Nature Communications、Light: Science & Applications、B&B、EST等發(fā)表SCI論文60余篇，論文H-index為26；以第一發(fā)明人授權(quán)國家發(fā)明專利9項，實現(xiàn)轉(zhuǎn)化與應(yīng)用3項。

近5年發(fā)表的同行評議論文（^#共同一作；^*通訊）：

1. H.H. Zhu, J. Zou, H. Zhang, Y.Z. Shi, S.B. Luo, N. Wang, H. Cai, L.X. Wan, B. Wang, X.D. Jiang^*, J. Thompson, X.S. Luo, X.H. Zhou^*, L.M. Xiao^*, W. Huang, L Patrick, M. Gu^*, L.C. Kwek^*, and A. Q. Liu^*. Space-efficient optical computing and an integrated chip of diffractive neural network. Nature Communications, 2022, 13, 1044.

2. Qian Zhu, Xiaohong Zhou^*. A colorimetric sandwich-type bioassay for SARS-CoV-2 using a hACE2-based affinity peptide pair. Journal of Hazardous Materials, 2022, 425, 127923.

3. Jinchuan Liu, Yunpeng Xing, Boyuan Xue, Xiaohong Zhou^*. Nanozyme enhanced paper-based biochip with a smartphone readout system for rapid detection of cyanotoxins in water. Biosensors and Bioelectronics, 2022, 205, 114099.

4. Lanhua Liu^#, Xuejun Zhang^#, Qian Zhu^#, Kaiwei Li, Yun Lu, Xiaohong Zhou^*, Tuan Guo^*. Ultrasensitive detection of endocrine disruptors via superfine plasmonic spectral combs. Light: Science and Applications, 2021, 10, 181.

5. Qian Zhu, Lanhua Liu, Ruoyu Wang, Xiaohong Zhou^*. A split aptamer (SPA)-based sandwich-type biosensor for facile and rapid detection of streptomycin. Journal of Hazardous Materials, 2021, 403, 123941.

6. Yihan Yang, Jinchuan Liu, Xiaohong Zhou^*. A CRISPR-based and post-amplification coupled SARS-CoV-2 detection with a portable evanescent wave biosensor. Biosensors and Bioelectronics, 2021, 190, 113418.

7. Jinchuan Liu, Yihan Yang, Qian Zhu, Zhanhui Wang, Guanjiu Hu, Hanchang Shi, Xiaohong Zhou^*. ELISA-Based Method for Variant-Independent Detection of Total Microcystins and Nodularins via a Multi-immunogen Approach. Environmental Science & Technology, 2021, 55, 19, 12984-12993.

8. Jinchuan Liu, Yunpeng Xing, Xiaohong Zhou^*, George Y. Chen^*, Hanchang Shi. Light-sheet skew rays enhanced U-shaped fiber-optic fluorescent immunosensor for microcystin-LR. Biosensors and Bioelectronics, 2021, 176, 112902.

9. Yangyang Chen^#, Qian Zhu^#, Xiaohong Zhou^*, Ruoyu Wang, Zhenchuan Yang. Reusable, facile, and rapid aptasensor capable of online determination of trace mercury. Environmental International, 2021, 146, 106181.

10. Jinbiao Ma, Manman Du, Can Wang^*, Xinwu Xie^*, Hao Wang, Tie Li^*, Shixing Chen, Lixia Zhang, Shun Mao, Xiaohong Zhou^*, Min Wu. Rapid and sensitive detection of Mycobacterium tuberculosis by an enhanced nanobiosensor. ACS Sensors, 2021, 6(9), 3367-3376.

11. Xiaohong Zhou^*, Abdul Ghaffar Memon, Weiming Sun, Fang Fang, Jinsong Guo^*. Fluorescent probe for Ag+ detection using SYBR GREEN I and C-C mismatch. Biosensors, 2021, 11, 6.

12. Weiming Sun, Lanhua Liu, Abdul Ghaffar Memon, Xiaohong Zhou^*, Hongwei Zhao^*. Waveguide-based fluorescent immunosensor for the simultaneous detection of carbofuran and 3-hydroxy-carbofuran. Biosensors, 2020, 10, 191. Selected as Title Story.

13. Xiaohong Zhou^*, Qian Zhu, Yihan Yang. Aptamer-integrated nucleic acid circuits for biosensing: Classification, challenges and perspectives. Biosensors and Bioelectronics, 2020, 165, 112422.

14. Xuewen Yi, Zhanqi Gao, Lanhua Liu, Qian Zhu, Guanjiu Hu^*, Xiaohong Zhou^*. Acute toxicity assessment of drinking water source with luminescent bacteria: Impact of environmental conditions and a case study in Luoma Lake, East China. Frontier Environmental Science and Engineering, 2020, 14(6), 109.

15. Yunpeng Xing, Qian Zhu, Xiaohong Zhou^*, Peishi Qi. A dual-functional smartphone-based sensor for colorimetric and chemiluminescent detection: A case study for fluoride concentration mapping. Sensors and Actuators B: Chemical, 2020, 319, 128254.

16. Yunpeng Xing, Qian Zhu, Xiaohong Zhou^*, Peishi Qi^*. A gold nanoparticle-based colorimetric mercury(II) biosensor using a DNA probe with phosphorothioate RNA modification and exonuclease III-assisted signal amplification. Microchimica Acta, 2020, 187, 214.

17. Abdul Ghaffar Memon, Yunpeng Xing, Xiaohong Zhou^*, Ruoyu Wang, Lanhua Liu, Siyu Zeng^*, Miao He^*, Mei Ma. Ultrasensitive colorimetric aptasensor for Hg2+ detection using Exo-III assisted target recycling amplification and unmodified AuNPs as indicators. Journal of Hazardous Materials, 2020, 384, 120948.

18. Ruoyu Wang^#, Qiansen Zhang^#, Yi Zhang, Hanchang Shi, Kim Truc Nguyen, Xiaohong Zhou^*. Unconventional split aptamers cleaved at functionally essential sites preserve biorecognition capability. Analytical Chemistry, 2019, 91, 15811-15817. Selected as Supplementary Cover Article.

19. Kaidong Xia, Zhihong Li, Xiaohong Zhou^*. Ultrasensitive detection of a variety of analytical targets based on a functionalized low-resistance AuNPs/beta-Ni(OH)₂ nanosheets/Ni foam sensing platform. Advanced Functional Materials, 2019, 29, 1904922.

20. Ruoyu Wang, Xiyu Zhu, Yunpeng Xing, Abdul Ghaffar Memon, Hanchang Shi, Xiaohong Zhou^*. Multitag-regulated cascade reaction: A generalizable ultrasensitive microRNA biosensing approach for cancer prognosis. ACS Applied Materials & Interface, 2019, 11, 36444-36448.

21. Yangyang Chen, Jinchuan Liu, James S. Wilkinson^*, Xiaohong Zhou^*. Optical biosensors based on refractometric sensing schemes: A review. Biosensors and Bioelectronics, 2019, 144, 111693.

22. Ruoyu Wang, Xueqi Wu, Xiyu Zhu, Hanchang Shi, Xiaohong Zhou^*. A photoregulated split aptaswitch for small molecules with improved sensitivity. Chemical Communications, 2019, 55, 9555-9558.

23. Lanhua Liu, Xiaohong Zhou^*, Yun Lu, Hanchang Shi, Mei Ma, Tong Yu. Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water samples. Environment International, 2019, 132, 105091.

24. Qian Zhu, Lanhua Liu, Xiaohong Zhou^*, Mei Ma. In silico study of molecular mechanisms of action: Estrogenic disruptors among phthalate esters. Environmental Pollution, 2019, 255, 113293.

25. Xiyu Zhu, Ruoyu Wang, Kaidong Xia, Xiaohong Zhou^*, Hanchang Shi. Nucleic acid functionalized fiber optic probes for sensing in evanescent wave: optimization and application. RSC Advances, 2019, 9, 2316-2324.

26. Abdul Ghaffar Memon, Xiaohong Zhou^*, Yunpeng Xing, Ruoyu Wang, Lanhua Liu, Mohsin Khan, Miao He^*. Label-free colorimetric nanosensor with improved sensitivity for Pb²⁺ in water by using a truncated 8-17 DNAzyme. Frontiers of Environmental Science & Engineering, 2019, 13, 12.

27. Lanhua Liu^#, Didi Shan^#, Xiaohong Zhou, Hanchang Shi, Baodong Song, Floris Falke, Arne Leinse, R.G. Heideman. TriplexTM waveguide-based fluorescence biosensor for multichannel environmental contaminants detection. Biosensors and Bioelectronics, 2018, 106, 117-121.

28. Jinchuan Liu, Xiaohong Zhou^*, Hanchang Shi. An optical biosensor-based quantification of microcystin synthetase A gene: Early warning of toxic cyanobacterial blooming. Analytical Chemistry, 2018, 90, 2362-2368.

29. Lanhua Liu, Xiaohong Zhou^*, Ruiman Ma, Miao He, Hanchang Shi, Qian Yi. High-throughput biomolecular interaction analysis probing by an array fluorescent biosensor platform, Sensors and Actuators B: Chemical, 2018, 259,888-893.

30. Qian Zhu, Lanhua Liu, Yunpeng Xing, Xiaohong Zhou^*. Duplex functional G-quadruplex/NMM fluorescent probe for label-free detection of lead(II) and mercury(II) ions, Journal of Hazardous Materials, 2018, 355, 50-55.

31. Ruoyu Wang, Xiaohong Zhou^*, Bo Liedberg, Xiyu Zhu, Abdul Ghaffar Memon, Hanchang Shi. Screening criteria for qualified antibiotic targets in unmodified gold nanoparticles-based aptasensing. ACS Applied Materials & Interfaces, 2017, 9, 35492–35497.

32. Xiyu Zhu, Ruoyu Wang, Xiaohong Zhou^*, Hanchang Shi. Free-energy-driven lock/open assembly-based optical DNA sensor for cancer-related microRNA detection with a shortened time-to-result, ACS Applied Materials & Interface, 2017, 9, 25789-25795.

33. Lanhua Liu, Xiaohong Zhou*, Yun Lu^*, Didi Shan, Bi Xu, Miao He, Hanchang Shi, Yi Qian. Facile screening of potential xenoestrogens by an estrogen receptor-based reusable optical biosensor. Biosensors and Bioelectronics, 2017, 97, 16-20.

34. Lanhua Liu, Xiaohong Zhou^*, James S. Wilkinson, Ping Hua^*, Baodong Song, Hanchang Shi. Integrated optical waveguide-based fluorescent immunosensor for fast and sensitive detection of microcystin-LR in lakes: optimization and analysis. Scientific Reports, 2017, 7: 3655.

35. Ruoyu Wang, Xiaohong Zhou^*, Xiyu Zhu, Chao Yang, Lanhua Liu, Hanchang Shi. Isoelectric bovine serum albumin: Robust blocking agent for enhanced performance in optical-fiber based DNA sensing. ACS Sensors. 2017, 2(2): 257–262.

36. Abdul Ghaffar Memon, Xiaohong Zhou^*, Jinchuan Liu, Ruoyu Wang, Lanhua Liu, Bofan Yu, Miao He^*, Hanchang Shi. Utilization of unmodified gold nanoparticles for label-free detection of mercury (II): Insight into rational design of mercury-specific oligonucleotides. Journal of Hazardous Materials, 2017, 321, 417-423.

37. Lanhua Liu, Xiaohong Zhou^*, Mifang Lu, Mingkai Zhang, Chao Yang, Ruiman Ma, Abdul Ghaffar Memon, Hanchang Shi, Yi Qian. An array fluorescent biosensor based on planar waveguide for multi-analyte determination in water samples. Sensors and Actuators B: Chemical, 2017, 240, 107-113.